Infant jaundice is a yellow discoloration in a newborn baby's skin and eyes. The condition occurs because the baby's blood contains an excess of bilirubin (bil-ih-ROO-bin), a yellow-colored pigment of red blood cells. Infant jaundice is a common condition, particularly in babies born before 36 weeks gestation (preterm babies). Infant jaundice usually occurs because a baby's liver isn't mature enough to get rid of bilirubin in the bloodstream. In some cases, an underlying disease may cause jaundice.

Treatment of infant jaundice often isn't necessary, and most cases that need treatment respond well to noninvasive therapy. Although complications are rare, severe infant jaundice or poorly treated jaundice can cause brain damage.